7 Best Flea & Tick Treatments for Dogs in 2025

Fleas and ticks are a relentless threat that constantly looms over your beloved dog, looking for chances to infect them. Therefore, protection against these pesky parasites is crucial. Fortunately, there is a plethora of flea and tick treatments in the market to help you do just that. However, selecting one from the myriad of options can be overwhelming for many dog parents.
In this blog, we’ll help simplify this selection process by discussing the top options among the various flea and tick treatment methods. We’ll also include the factors to keep in mind while making the selection.
So, stick till the end!
Top 7 Flea and Tick Treatments for Dogs
In this segment, we’ll discuss the best flea and tick treatments across various treatment methods and give valuable recommendations.
1. Broad-Spectrum:
Simparica Trio

Simparica Trio is a fast-acting, broad-spectrum flea and tick treatment for dogs. With Sarolaner, Moxidectin, and Pyrantel as the active ingredients, these flavored chewable tablets start killing fleas within 4 hours and prevent flea infestations. Suitable for dogs and puppies from 8 weeks of age and weighing at least 2.8 lbs, Simparica Trio is also indicated for the prevention of heartworm disease.
It treats and controls tick infestations caused by Gulf Coast ticks, deer ticks, American dog ticks, lone star ticks, brown dog ticks, and Asian long-horned ticks. Additionally, by killing deer ticks, it prevents Lyme disease. Furthermore, the monthly treatment treats and controls roundworms and hookworms. The wide range of protection Simparica Trio offers makes it the true broad-spectrum king!
Other recommendation: Nexgard Spectra
2. Topical Treatment:
Frontline Plus for Dogs

Frontline Plus is a reliable monthly topical treatment with fipronil and S-methoprene as the active ingredients. This easy-to-administer treatment is designed to protect dogs and puppies from 8 weeks of age, weighing at least 5 lbs, against a range of parasites. The potent treatment kills all the life stages of fleas and effectively prevents flea infestations. Plus, it kills fleas that may cause flea allergy dermatitis.
Furthermore, the topical solution kills all life stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks. It is safe to use in breeding, pregnant, and lactating dogs. Plus, it covers chewing lice, sarcoptic mange, and aids in the prevention of Lyme disease.
Other recommendations: Bravecto Spot-on and Vectra 3D
3. Oral Treatment:
Bravecto Chews

Bravecto Chews is a palatable fast-acting oral treatment for dogs. One dose of Bravecto protects the dogs against multiple parasites for 12 weeks. With Fluralaner as the active ingredient, it starts killing fleas within 2 hours of administration.
Plus, it treats and controls infestations of black-legged ticks, American dog ticks, brown dog ticks, and Asian long-horned ticks for 12 weeks. It also treats and controls lone star tick infestations for 8 weeks in dogs and puppies from 6 months of age, weighing at least 4.4 lbs.
Other recommendations: Nexgard for Dogs & Credelio for Dogs
4. Collar:
Seresto Collar

Seresto Collar is a long-lasting and innovative flea and tick collar for dogs. This easy-to-use collar protects dogs and puppies from 7 weeks of age against fleas, ticks, and lice. The odorless and non-greasy collar features a polymer matrix technology that ensures the active ingredients are released slowly and consistently. With this slow-release technology, it protects the dog continuously for 8 months.
Other recommendations: Bayopet Tick & Flea Collar and Bob Martin Clear Tick & Flea Collar
5. Shampoo:
Karbawash Shampoo

Karbawash Shampoo is a potent wettable powder shampoo formulated to protect dogs against a range of external parasites. The formula contains Carbaryl as its active ingredient that eliminates fleas and ticks by targeting their nervous system. This solution can also be used as a dip to control fleas and ticks on dogs.
Other recommendation: Malaseb Shampoo For Dogs
6. Spray:
Aristopet Flea & Tick Spray

Aristopet Flea & Tick Spray is a gentle and quick-drying spray for protection against fleas and ticks. Suitable for dogs and puppies over 12 weeks of age, the spray contains highly synergized natural Pyrethrins. It is ideal to control fleas and adult brown dog ticks.
Other recommendation: Effipro Spray
7. Powder:
Ultrum Flea & Tick Powder

It’s an innovative, perfumed, talc-based powdered treatment to protect dogs against multiple parasites. This easy-to-use powder contains Propoxur as its active ingredient and controls fleas, ticks, feather mites, red mites, and lice on dogs. The powder can be dusted on the dog or onto their bedding and sleeping area.
Other recommendation: Aristopet Flea Powder
Factors to Consider While Selecting Flea & Tick Treatment
These are the crucial factors that will help you select the right flea and tick treatment for your dog.
- Suitability: Make sure that the treatment you select matches your dog’s age, weight, and health condition.
- Pet’s preference: Keep in mind your pet’s comfort while making the selection.
- Your climate: Consider the prevalence of fleas and ticks in your area.
- Safety: Check for any potential side effects or risks associated with the treatment.
- Cost: Compare the prices of the treatments and consider your budget.
- Vet recommendation: Consult your vet for personalized advice. They will suggest the best treatment option depending on your dog’s condition and medical history.
Parting Words
These are the most preferred and recommended flea and tick treatments. Keep in mind the selection factors discussed above, and you can make the correct selection. However, if you have any doubts, it’s best to consult your vet.
